Treating Vehicular Hyperthermia in Children - Patient Care - @

How to Treat Vehicular Hyperthermia in Children



Ramsey C. Tate, MD | William Selde, MD | From the July 2013 Issue | Friday, June 14, 2013


Multimedia Thumb

Video Reenactment: Hyperthermia in Child Locked Inside Car

Video shows the tragic consequences of leaving a child locked inside a hot car.
more >

Vehicular hyperthermia is an uncommon but preventable cause of heat stroke in young children. As children are placed out of sight in the back seat of vehicles, the incidence of deaths due to vehicular hyperthermia has increased. Young children trapped in hot vehicles may present with heat stroke. They have core body temperatures of greater than 100˚ F and have neurologic dysfunction. Acute management primarily requires cardiovascular resuscitation for dehydration or shock and rapid cooling.

On a typical weekday morning, a busy mother places her 10-month-old daughter in one of the rear-facing car seats in the family’s SUV and sets off to drop her daughter at daycare before heading to work.  Fatigued and distracted, the mother stops to get gas and then drives to her office, grabs her purse from the front passenger seat, and heads in to start her workday. Twenty minutes later, she receives a call from the daycare asking if her daughter will be absent today. Panicked, the mother realizes that the sleeping baby is still in her car seat in the parked car in the sun. When she reaches the car the baby is hot, difficult to arouse and breathing fast. She calls 9-1-1.

The EMS providers who arrive on scene recognize that the baby is suffering from heat stroke.  This brings up some questions. Why are the crews seeing this more often? What is the pathophysiology of vehicular hyperthermia? What are the most effective management strategies in the field for BLS vs. ALS providers?

Vehicular hyperthermia in young children is an increasing cause of mortality. Introduction of guidelines encouraging parents to restrain young children in backseats were introduced in the 1990s as injuries and fatalities from airbag deployments became more common. As an unintended consequence of this very successful public health intervention, combined with increasing distraction from cell phones and busy schedules, the frequency of children being left in cars increased because children in car seats are now less visible to drivers.

Prior to the mid-1990s, there were less than 10 pediatric deaths per year in the U.S. due to vehicular hyperthermia. Between 1998 and 2012, that number increased to an estimated 559, an average of 38 deaths per year. More than two-thirds of these deaths were in children younger than age 3. The most common reason given by caregivers of these victims in media reports is that they forgot the child was in the vehicle. Other reasons included that the child was playing unattended in the vehicle or that the caregiver left the child in the vehicle intentionally.

The burden of deaths due to vehicular hyperthermia also reflects weather patterns, as major metropolitan areas in the southern U. S. experience a higher proportion of deaths.1-3

The air temperature inside vehicles rises dramatically, an effect poorly understood by many parents and caregivers. In studies of the rate of increase of vehicle interior temperatures, the air temperature inside a vehicle parked in the sun with variable outside temperatures increased by approximately 20˚ in 10 minutes. By 20 minutes, the inside air temperature was 29˚ higher than ambient temperatures. By 60 minutes, a variety of vehicle types and ambient temperatures will reach similar peak interior temperatures of 140–180˚ F.1-2, 4-5 Even a brief entrapment in a vehicle can expose a child to heatstroke (having a temperature above 104° F), but fatalities generally result from prolonged heat exposure. In a review of 171 pediatric deaths due to vehicular hyperthermia, the duration of heat exposure averaged 4.6 hours with the shortest recorded fatal exposure of 15 minutes. The core body temperature of deceased victims was between 102.9–109˚ F.2

Pathophysiology of Hyperthermia
Although vehicular entrapment quickly results in hyperthermia in victims of all ages, children are especially vulnerable to the effects of heat stroke. Compared to adults, they have a more susceptible surface area that can absorb heat and immature thermoregulation. Additionally, young children strapped into a car seat are both developmentally and physically unable to extricate themselves from a vehicle, remove clothing to help manage heat or drink fluids to manage dehydration.

Heat stroke is the most severe form of heat illness. It usually consists of a core body temperature greater than or equal to 104˚ F and neurologic dysfunction, such as disorientation, delirium, seizures, or coma. The pathophysiology of heat stroke in children relates to the duration of exposure to heat. At the onset of heat stress, cardiac output increases and circulation is shunted peripherally to vasodilate skin and muscle to facilitate heat loss. Hyperthermia develops as the child is unable to dissipate heat with prolonged exposure and can no longer maintain a normal core body temperature. As it progresses, dehydration and electrolyte abnormalities develop, particularly hypernatremia due to water loss and hypocalcemia due to skeletal muscle degradation. These electrolyte abnormalities affect cardiac contractility and conduction, and impede the child’s ability to maintain an elevated cardiac output. In the presence of dehydration and vasodilation, this drop in cardiac output leads to hypotension.

As the duration of exposure increases, endothelial damage occurs to the microvasculature and children may develop cutaneous signs of coagulopathy, including petechiae and purpura. Terminal hyperthermia results in cardiac arrhythmias and deep gasping.6-8 In a series of autopsies of children who died from vehicular hyperthermia, the most consistent finding was intrathoracic petechiae, presumed to be due to deep gasping.9 Although victims of heat stroke may progress to cerebral edema, multiorgan hemorrhage, and necrosis or rhabdomyolysis, these injuries are not believed to be present during acute heat stroke.9

Table 1: BLS & ALS Treatment of Hyperthermia



·         Extricate from vehicle.

·         Provide oxygen and bag-valve mask.

·         CPR

·         Obtain rectal temperature.

·         Strip to bare skin.

·         Fan with cold air and mist with water or saline.

·         Apply ice packs to axilla, groin and neck.


·         Perform ECG interpretation.

·         Provide advanced cardiac life support drugs.

·         Obtain point-of-care glucose.

·         Administer cold IV fluid.

·         Intubate or place supraglottic airway device.

·         Administer midazolam for shivering or seizure.

Treatment of hyperthermia should begin with a thorough history and physical assessment. Often, but not always, the history or scene circumstances will provide clues to the cause of the patient’s condition. It’s important to initially keep a broad differential diagnosis, including infectious causes, toxic ingestions or exposures, or status epilepticus. Accordingly, the initial physical assessment and interventions should focus on routine resuscitation of airway, breathing and circulation.

Airway: Depending on the degree of hyperthermia and altered mental status, the child may require basic and advanced airway maneuvers, including bag-valve mask ventilation, supraglottic airway or endotracheal tube insertion, to maintain their airway and breathing.7,10

Breathing: All patients with suspected hyperthermia and altered mental status should receive treatment with supplemental oxygen because of the patient’s increased metabolic rate in the face of heat stress.

Circulation: At least one intraosseous (IO) or IV access point should be established. Children with vehicular hyperthermia are often only mildly hypovolemic, because there has been no exertion. An initial fluid bolus of 20 mL/Kg of either chilled or tepid isotonic crystalloid is appropriate initial treatment.11 Given the potential for electrolyte abnormalities, a 12-lead ECG may add to clinical management by ALS providers. The most common ECG finding in hyperthermia is sinus tachycardia; however, abnormal intervals, peaked t-waves, bradycardia, or a widened QRS complex are concerning for electrolyte abnormalities. For hyperthermic patients in shock, vasoactive agents, including calcium gluconate delivered via IV or intramuscularly, may need to be initiated to maintain normotension.7,11

Disability: A point-of-care blood glucose should be done to exclude hypoglycemia as a cause of altered mental status.10

Exposure: Core temperature should be measured rectally as rapidly as possible. Axillary, oral and tympanic temperatures are not accurate enough for diagnosis or treatment of hyperthermia.7,10–11 The goal of treatment is the initiation of cooling to a core temperature of 100° F as quickly as safely possible. Because morbidity and mortality are directly related to the duration of hyperthermia, aggressive cooling should begin in the field.10–13 Antipyretics do not have a role in treating environmental hyperthermia.

Heat stroke requires active cooling, but there’s no evidence-based best method for cooling in the pediatric population. Data from small trials and expert consensus suggest that evaporative cooling is the most appropriate and rapid method in the field.

The patient should be removed from the vehicle and stripped to bare skin. Room temperature water is effective for evaporative cooling and better tolerated than ice water. Once exposed, the patient should be sprayed with water or saline while being fanned manually or, preferably, by the ambulance fan or air conditioner. Evaporative cooling should be augmented with ice packs placed in the axilla, groin, and around the neck if the patient will tolerate it. To prevent hypothermia, cooling should be stopped once the goal temperature of 100° F has been achieved.  Midazolam 0.05–0.1 mg/kg IV/IO can be given for shivering or seizure. Shivering should be actively managed because it slows the rate of cooling.7, 10-11 Since patients will cool during transport, the concern for hyperthermia needs to be clearly conveyed to the receiving staff because the initial core temperature measured by hospital staff may be below 104° F.

Milder cases of heat illness can be treated by simply removing the patient from the vehicle and placing them in a cool environment. Oral or IV rehydration with an isotonic electrolyte solution may also aid recovery from heat exhaustion.

Transport: Hyperthermia requires recognition, stabilization, and initiation of treatment in the field, but this shouldn’t delay transport to definitive care. Local destination protocols for pediatric patients should be followed but, in general, these patients will benefit from being taken to a hospital with PICU facilities if one is available. Unstable patients should be taken to the nearest emergency department approved for children. Some patients may initially appear well after confinement in a hot vehicle, but if they have any elevation in core temperature, these patients should be evaluated by an emergency department to rule out electrolyte abnormalities or muscle breakdown that may not be apparent on initial exam and could develop hours after exposure. Children who have a normal mental status, were not exposed to very high temperatures and have a normal core temperature may be released to a reliable caregiver with advice to seek evaluation by their primary care physician, if allowed by local protocol.

1. Null J. (May 17, 2013). Hyperthermia deaths of children in vehicles. In Department of Geosciences, San Francisco State University. Retrieved April 20, 2013, from
2. Booth JN, Davis GG, Waterbor J, et al.. Hyperthermia deaths among children in parked vehicles: An analysis of 231 fatalities in the United States, 1999–2007. Forensic Sci. Med. Pathol. 2010;6(2):99–105.
3. Grundstein A, Null J, Meentemeyer V. Weather, geography, and vehicle-related hyperthermia in children. Geogr. Rev. 2011;101(3):353–370.
4. Grundstein A, Dowd J, Meentemeyer V. Quantifying the heat-related hazard for children in motor vehicles. Bull. Am. Meteorol. Soc. 2010;91(9):1183–1891.
5. McLaren C. Heat stress from enclosed vehicles: Moderate ambient temperatures cause significant temperature rise in enclosed vehicles. Pediatrics. 2005;116(1):e109–e112.
6. Palmiere C, Mangin P. Hyperthermia and postmortem biochemical investigations. Int. J. Legal Med. 2012;127(1):93–102.
7. Bouchama A, Knochel JP. Heat stroke. N. Engl. J. Med. 2002;346(25):1978–1988.
8. Jardine DS. Heat illness and heat stroke. Pediatr. Rev. 2007;28(7):249–258.
9. Krous HF, Nadeau JM, Fukumoto RI, et al. Environmental hyperthermic infant and early childhood death: Circumstances, pathologic changes, and manner of death. Am. J. Forensic Med. Pathol. 2001;22(4):374–382.
10. Bouchama A, Dehbi M, Chaves-Carballo E. Cooling and hemodynamic management in heatstroke: practical recommendations. Crit. Care Lond. Engl. 2007;11(3):R54.
11. Strange GR, Prendergast HM. Chapter 140: Heat and cold illness. Pediatr. Emerg. Med. Retrieved April 22, 2013 from
12. Heled Y, Rav-Acha M, Shani Y, et al. The “golden hour” for heatstroke treatment. Mil. Med. 2004;169(3):184–186.
13. Vicario SJ, Okabajue R, Haltom T. Rapid cooling in classic heatstroke: effect on mortality rates. Am J Emerg Med. 1986;4(5):394–398.

Video Reenactment: Hyperthermia in Child Locked Inside Car

Connect: Have a thought or feedback about this? Add your comment now
Related Topics: Patient Care, Special Patients, treating hyperthermia, purpura, petechiae, pediatrics, microvasculature, hypothermia, Hyperthermia, hot cars, heat stroke, endothelial damage, electrolyte imbalance, dehydration, core body temperature, coagulopathy, children, Jems Features


Ramsey C. Tate, MD

Ramsey C. Tate, MD, is a pediatric emergency medicine fellow at the University of New Mexico. She can be reached at


William Selde, MD

William Selde, MD, is a board certified emergency medicine physician at the Wyoming Medical Center and a graduate of the EMS fellowship at the University of New Mexico. He can be reached at,


What's Your Take? Comment Now ...

Buyer's Guide Featured Companies

Featured Careers & Jobs in EMS

Get JEMS in Your Inbox


Fire EMS Blogs

Blogger Browser

Today's Featured Posts


EMS Airway Clinic

Innovation & Advancement

This is the seventh year of the EMS 10 Innovators in EMS program, jointly sponsored by Physio-Control and JEMS.
More >

Multimedia Thumb

Pennsylvania Paramedic Killed in the Line of Duty

West End Ambulance medic killed at accident scene.
Watch It >

Multimedia Thumb

Wesleyan Students Hospitalized for Overdose

11 students transported to local hospitals.
Watch It >

Multimedia Thumb

Denver Medic's Family Says Job Stress Contributed to Suicide

Veteran of over 25 years took her own life after a call.
Watch It >

Multimedia Thumb

Rigs Going in Service from EMS Today 2015

Snap shots of some of the vehicles at EMS Today that will be on the streets soon
More >

Multimedia Thumb

Florida Hospital Fire

Fire halts construction project at Tampa cancer center.
More >

Multimedia Thumb

LMA MAD Nasal™

Needle-free intranasal drug delivery.
Watch It >

Multimedia Thumb

Braun Ambulances' EZ Door Forward

Helps to create a safer ambulance module.
Watch It >

Multimedia Thumb

Field Bridge Xpress ePCR on iPad, Android, Kindle Fire

Sneak peek of customizable run forms & more.
Watch It >

More Product Videos >