Meridian Introduces Single-Vial Dose of CYANOKIT

Now with a longer shelf life

 

 
 
 

| Wednesday, November 2, 2011


Meridian Medical Technologies, Inc., a Pfizer company, has introduced a new single-vial dose of CYANOKIT® (hydroxocobalamin for injection) 5 g. In this new presentation of CYANOKIT®, the entire starting dose of 5 g hydroxocobalamin is now provided in a single vial, replacing the previous kit containing two, 2.5-g vials. CYANOKIT® is approved by the U.S. Food and Drug Administration for the treatment of either known or suspected cyanide poisoning.[i]
Cyanide (CN) can be released by virtually any material containing carbon and nitrogen when burned under high temperature and low oxygen conditions.[ii],[iii] There is high potential for CN toxicity at many fire scenes due to the increased use of synthetic materials that produce CN during combustion in closed-space fires.2,3 Moderate to high concentrations of cyanide can cause severe injury and death within minutes.[iv] Therefore Cyanide poisoning is a life-threatening situation that requires immediate medical attention.
There’s currently no diagnostic test to confirm CN poisoning in the field within the limited window for initiating potentially lifesaving intervention.2,3 In addition, CN poisoning can be difficult to differentiate with carbon monoxide (CO) poisoning due to common signs and symptoms.2 Because CN poisoning prevents cells from using oxygen (O2), signs and symptoms of CN poisoning also mimic those of O2 deprivation.[v]
Cyanide poisoning may result from inhalation, ingestion, or dermal exposure and should be suspected in smoke inhalation victims if they’re exposed to fire or smoke in an enclosed area, present with soot around the mouth, nose, or back of mouth or have an altered mental status.
CYANOKIT® is administered intravenously after being reconstituted with sodium chloride for injection. Hydroxocobalamin, the main component in CYANOKIT®, strongly binds the cyanide directly, forming a natural form of vitamin B12, cyanocobalamin, which is excreted in the urine.4
In addition to the full starting dose of CYANOKIT® 5 g now contained in a single vial, the new packaging is more compact than the previous packaging and the new dose also features a 20 percent greater shelf life (36 months from the date of formulation).
To learn more about CYANOKIT®, please visit www.CYANOKIT.com.

[i] Cyanokit [package insert]. Columbia, MD: Meridian Medical Technologies, Inc.; 2011.
[ii] Agency for Toxic Substances and Disease Registry. Cyanide toxicity. Am Fam Physician. 1993;48(1):107-114.
[iii] Alcorta R. Smoke inhalation & acute cyanide poisoning. In: Losavio K, ed. Smoke Inhalation & Hydrogen Cyanide Poisoning. San Diego, CA: JEMS Communications; 2004:6-17.
[iv] Eckstein M, Maniscalco PM. Focus on smoke inhalation— the most common cause of acute cyanide poisoning. Prehosp Disaster Med. 2006;21(2):s49-s55.
[v] Schnepp R. Where there’s fire—there’s smoke! In: Smoke: Cyanide and Carbon Monoxide: The Toxic Twins of Smoke Inhalation. Indianapolis, IN: Cyanide Poisoning Treatment Coalition; 2009:3-8

 




Connect: Have a thought or feedback about this? Add your comment now
Related Topics: News, Industry News

 
What's Your Take? Comment Now ...

Featured Careers & Jobs in EMS





 

Get JEMS in Your Inbox

 

Fire EMS Blogs


Blogger Browser

Today's Featured Posts

 

EMS Airway Clinic

Innovation & Progress

Follow in the footsteps of these inspirational leaders of EMS.
More >

Multimedia Thumb

Three Kentucky Firefighters Injured in Ice Bucket Challenge

Campbellsville tower ladder comes in contact with power lines.
Watch It >


Multimedia Thumb

NAEMT: Transforming EMS

A look inside at the Mobile Healthcare Paramedic system.
Watch It >


Multimedia Thumb

Austin-Travis County Community Health Paramedic Program

Overview of program provides operation and referral details.
Watch It >


Multimedia Thumb

Flight Paramedic’s Perfect Weekend

Carilion Lifeguard Flight Paramedic shares what would make his perfect weekend.
Watch It >


Multimedia Thumb

Numerous Rescues during Arizona Flooding

Severe flooding across the region prompted several rescues.
More >


Multimedia Thumb

Colorado Hiker Rescue

Injured hiker spent three hours in a crevice.
More >


Multimedia Thumb

Airlift at Swiss Train Derailment

Helicopters used to help reach the injured.
More >


Multimedia Thumb

Braun Ambulances' EZ Door Forward

Helps to create a safer ambulance module.
Watch It >


Multimedia Thumb

Field Bridge Xpress ePCR on iPad, Android, Kindle Fire

Sneak peek of customizable run forms & more.
Watch It >


Multimedia Thumb

The AmbuBus®, Bus Stretcher Conversion Kit - EMS Today 2013

AmbuBus®, Bus Stretcher all-hazards preparedness & response tool
Watch It >


Multimedia Thumb

LMA MAD Nasal™

Needle-free intranasal drug delivery.
Watch It >


More Product Videos >